| 1 | Dudley (NC) | 186 |
| 1) Jazmine Gooden | | 43.18 | 1 |
| 2) Maniya Stocks | | 47.84 | 26 |
| 3) Mykayla Wall | | 48.72 | 40 |
| 4) Jesika Richmond | | 49.64 | 55 |
| 5) Maurisha Cunningham | | 50.18 | 64 |
| Average Time: 47.91 Total Time: 3:59.56 1-5 Split: 7.00 |
| 6) Eryka Baker | | 52.14 | 115 |
| 7) Jermya Burgess | | 55.04 | 195 |
| 2 | Southeast Raleigh (NC) | 322 |
| 1) Sierra Fletcher | | 43.55 | 3 |
| 2) Charlonda Washington | | 45.62 | 11 |
| 3) Tonisha Williams | | 47.14 | 17 |
| 4) Jordan Gary | | 51.44 | 90 |
| 5) Tameia Morrison | | 55.24 | 201 |
| Average Time: 48.60 Total Time: 4:02.99 1-5 Split: 11.69 |
| 3 | Mallard Creek (NC) | 344 |
| 1) Sydney Whalen-Jenkins | | 44.80 | 7 |
| 2) Kaylan Parks | | 45.26 | 10 |
| 3) T'nai Wells | | 48.36 | 31 |
| 4) Kyla Smith | | 52.97 | 133 |
| 5) Maya Alexander | | 53.85 | 163 |
| Average Time: 49.05 Total Time: 4:05.24 1-5 Split: 9.05 |
| 4 | Parkland (NC) | 383 |
| 1) Kimani Davis | | 44.08 | 5 |
| 2) Siearra Emmerson | | 49.74 | 57 |
| 3) Amari Simington | | 50.60 | 73 |
| 4) Diamond Lyerly | | 52.23 | 117 |
| 5) Gabrielle Cain | | 52.94 | 131 |
| Average Time: 49.92 Total Time: 4:09.59 1-5 Split: 8.86 |
| 5 | Rocky Mount (NC) | 414 |
| 1) Nyana Edwards | | 47.34 | 22 |
| 2) Edwards Iyanna | | 48.04 | 27 |
| 3) Tanaka Coburn | | 51.14 | 86 |
| 4) Quaneshia Hardy | | 51.64 | 94 |
| 5) Keyasha Corey | | 54.74 | 185 |
| Average Time: 50.58 Total Time: 4:12.90 1-5 Split: 7.40 |
| 6) Amaya Dickens | | 58.34 | 293 |
| 7) Tyreia Joyner | | 59.24 | 318 |
| 6 | T.C. Roberson (NC) | 457 |
| 1) Annie Sherrill | | 49.64 | 54 |
| 2) Azyia Poore | | 50.64 | 74 |
| 3) Kali Endaya | | 51.14 | 85 |
| 4) Elizabeth Griffin | | 51.95 | 109 |
| 5) Caroline Nguyen | | 53.04 | 135 |
| Average Time: 51.28 Total Time: 4:16.41 1-5 Split: 3.40 |
| 6) Vittoria Duque | | 55.14 | 199 |
| 7 | Millbrook (NC) | 465 |
| 1) Tahlieah Sampson | | 49.04 | 43 |
| 2) Jada Rochelle | | 50.94 | 80 |
| 3) Taleah Kelly | | 51.74 | 97 |
| 4) Tahlieah Sampson | | 52.24 | 118 |
| 5) Kiana Stotts | | 52.74 | 127 |
| Average Time: 51.34 Total Time: 4:16.70 1-5 Split: 3.70 |
| 8 | Marvin Ridge (NC) | 477 |
| 1) Jorja Medders | | 44.95 | 8 |
| 2) Shaylee Cooney | | 51.43 | 89 |
| 3) Cassie Sullivan | | 51.93 | 107 |
| 4) Nina Van Blarcom | | 52.52 | 122 |
| 5) Samia Usmani | | 53.54 | 151 |
| Average Time: 50.87 Total Time: 4:14.37 1-5 Split: 8.59 |
| 6) Lauren Moulton | | 54.27 | 171 |
| 7) Kelsey Nicholls | | 54.94 | 192 |
| 9 | Cummings, Hugh M. (NC) | 481 |
| 1) Kayla Moore | | 43.79 | 4 |
| 2) Kenyae Majors | | 49.29 | 45 |
| 3) Jacquazha Nettles | | 52.09 | 112 |
| 4) Brianna McGowens | | 53.34 | 148 |
| 5) Kelsia Moore | | 54.34 | 172 |
| Average Time: 50.57 Total Time: 4:12.85 1-5 Split: 10.55 |
| 6) Lashonda Tate | | 54.34 | 173 |
| 10 | East Mecklenburg (NC) | 489 |
| 1) Nia Goodman | | 47.22 | 19 |
| 2) Icess Young | | 49.74 | 59 |
| 3) Icess Young | | 50.80 | 77 |
| 4) Essence Mcgee | | 52.54 | 124 |
| 5) Tselotte Sisay | | 55.44 | 210 |
| Average Time: 51.15 Total Time: 4:15.74 1-5 Split: 8.22 |
| 6) Aniyah Soto | | 56.44 | 242 |
| 7) Gloria Nzuzi | | 57.74 | 280 |